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Some heart conditions that CoQ10 may help include congestive heart failure , preventing blood vessel complications caused by heart bypass surgery, and high blood pressure. It assists in maintaining the normal oxidative state of LDL cholesterol, supports circulatory health and optimal functioning of the heart muscle.
Another study published in the journal Interactive CardioVascular and Thoracic Surgery found that patients who took CoQ10 for two weeks before undergoing bypass surgery strengthened the heart and reduced the risk of ventricular arrhythmias post-surgery.
In that same study, the researchers concluded that none of the clinical trials reported any adverse events. However, they point out that better-quality long-term clinical trials need to be done to zero in on the role of CoQ10 for this use.
And according to Splaver, CoQ10 is recommended at times for those patients using cholesterol-lowering statins , such as Crestor rosuvastatin and Lipitor atorvastatin , as these statins lower your natural levels of CoQ This drop can lead to muscle aches and pains. Chronic systemic inflammation is present in many metabolic diseases, including type 2 diabetes, obesity, cardiovascular disease, and nonalcoholic fatty liver disease.
A review of nine studies on the effect of CoQ10 supplementation on inflammatory markers revealed that CoQ10 reduced the level of specific inflammatory markers of which there is nine total leading to a partial improvement in the inflammatory state of people with metabolic diseases. A study in the journal Atherosclerosis suggests that dementia could be predicted by serum CoQ10 levels.
Research is underway to investigate the use of CoQ10 for improving cognitive function in healthy older people. The study , conducted by researchers in Australia, will administer mg of ubiquinol or a placebo daily to people age 60 or older over a day period. A review of the literature on fatigue suggests that low levels of CoQ10 were consistently associated with fatigue.
And yet another study suggests that a combination of several supplements, including CoQ10, can help reduce fatigue and restore mitochondrial function in people with chronic disease. As for easing migraines, a study in the journal Nutritional Neuroscience showed that CoQ10 supplementation can improve migraines.
In the study, 45 women with episodic migraine took either mg of CoQ10 or a placebo daily, in addition to their regular prophylactic medication, for three months. Those with heart conditions, such as heart failure and angina, may benefit from taking a CoQ10 supplement. A review of 13 studies in people with heart failure found that mg of CoQ10 per day for 12 weeks improved blood flow from the heart Plus, supplementing has been shown to reduce the number of hospital visits and the risk of dying from heart-related issues in individuals with heart failure CoQ10 is also effective in reducing the pain associated with angina, which is chest pain caused by your heart muscle not getting enough oxygen For people with heart failure or angina, the typical dosage recommendation for CoQ10 is 60— mg per day When used alone or in combination with other nutrients, such as magnesium and riboflavin, CoQ10 has been shown to improve migraine symptoms.
It has also been found to ease headaches by reducing oxidative stress and free radical production, which may otherwise trigger migraines. CoQ10 decreases inflammation in your body and improves mitochondrial function, which helps reduce migraine-associated pain A three-month study in 45 women demonstrated that those treated with mg of CoQ10 per day experienced significant reductions in the frequency, severity and duration of migraines, compared to a placebo group For treating migraines, the typical dosage recommendation for CoQ10 is — mg per day As mentioned above, CoQ10 levels naturally deplete with age.
Thankfully, supplements can raise your levels of CoQ10 and may even improve your overall quality of life. Older adults with higher blood levels of CoQ10 tend to be more physically active and have lower levels of oxidative stress, which may help prevent heart disease and cognitive decline CoQ10 supplements have been shown to improve muscle strength, vitality and physical performance in older adults Both oxidative stress and mitochondrial dysfunction have been linked to the onset and progression of diabetes and diabetes-related complications Studies show that supplementing with CoQ10 helps reduce the production of free radicals, which are unstable molecules that can harm your health if their numbers get too high.
CoQ10 also helps improve insulin resistance and regulate blood sugar levels in people with diabetes. A week study in 50 people with diabetes found that those who received mg of CoQ10 per day had significant reductions in blood sugar, markers of oxidative stress and insulin resistance, compared to the control group Doses of — mg of CoQ10 per day appear to improve diabetes symptoms Oxidative damage is one of the main causes of both male and female infertility by negatively affecting sperm and egg quality 29 , For example, oxidative stress can cause damage to sperm DNA, potentially resulting in male infertility or recurrent pregnancy loss Research has found that dietary antioxidants — including CoQ10 — may help reduce oxidative stress and improve fertility in both men and women.
Supplementing with — mg per day of CoQ10 has been shown to improve sperm concentration, density and motility in men with infertility Similarly, these supplements may improve female fertility by stimulating ovarian response and help slow ovarian aging CoQ10 doses of — mg have been shown to help boost fertility CoQ10 supplements help reduce the inflammation associated with heavy exercise and may even speed recovery A 6-week study in German athletes found that those who supplemented with mg of CoQ10 daily experienced significant improvements in physical performance — measured as power output — compared to a placebo group CoQ10 has also been shown to reduce fatigue and increase muscle power in non-athletes Doses of mg per day appear to be most effective in boosting athletic performance in research studies Dosage recommendations for CoQ10 vary depending on individual needs and goals.
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